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• Activity deltas table
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Motif ID: POU5F1_SOX2{dimer}.p2

Z-value: 1.554

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr2_-_215949566	4.070		FN1	fibronectin 1
chr9_-_21340885	2.552	NM_021002	IFNA6	interferon, alpha 6
chr2_-_215998181	2.166		FN1	fibronectin 1
chr4_-_21155376	2.098	NM_001035004	KCNIP4	Kv channel interacting protein 4
chr12_-_10846435	2.068	NM_023919	TAS2R7	taste receptor, type 2, member 7
chr6_-_66346417	2.037	NM_198283	EYS	eyes shut homolog (Drosophila)
chr18_+_50646616	1.947	NM_004163	RAB27B	RAB27B, member RAS oncogene family
chr12_+_103221590	1.928	NM_001008394	EID3	EP300 interacting inhibitor of differentiation 3
chr9_+_21399132	1.906	NM_002170	IFNA8	interferon, alpha 8
chr7_+_90176647	1.788	NM_012395	CDK14	cyclin-dependent kinase 14
chr4_-_149577404	1.769
chr18_-_56190980	1.693	NM_005912	MC4R	melanocortin 4 receptor
chr9_-_21229975	1.659	NM_002172	IFNA14	interferon, alpha 14
chr4_+_114433551	1.644		ANK2	ankyrin 2, neuronal
chr12_-_88573949	1.610	NM_001001323 NM_001682	ATP2B1	ATPase, Ca++ transporting, plasma membrane 1
chr3_-_56784634	1.539	NM_001128616	ARHGEF3	Rho guanine nucleotide exchange factor (GEF) 3
chr2_+_113479919	1.506	NM_014440	IL1F6	interleukin 1 family, member 6 (epsilon)
chr9_-_21197141	1.494	NM_002171	IFNA10	interferon, alpha 10
chr13_+_96592051	1.481		MBNL2	muscleblind-like 2 (Drosophila)
chr11_-_121492010	1.397	NM_001001786	BLID	BH3-like motif containing, cell death inducer
chr2_+_183316574	1.372		DNAJC10	DnaJ (Hsp40) homolog, subfamily C, member 10
chr9_-_21192201	1.312	NM_021057	IFNA7	interferon, alpha 7
chr10_-_98263434	1.294	NM_012465	TLL2	tolloid-like 2
chr9_-_21132143	1.290	NM_002177	IFNW1	interferon, omega 1
chr1_+_245835478	1.273	NM_001001914	OR2G3	olfactory receptor, family 2, subfamily G, member 3
chr20_-_9767406	1.272	NM_020341 NM_177990	PAK7	p21 protein (Cdc42/Rac)-activated kinase 7
chr1_-_150328153	1.239	NM_001008536	TCHHL1	trichohyalin-like 1
chr8_-_93099040	1.210	NM_175636	RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr9_+_2707525	1.206	NM_133497	KCNV2	potassium channel, subfamily V, member 2
chr2_-_20390601	1.192	NM_015317	PUM2	pumilio homolog 2 (Drosophila)
chr2_-_200038055	1.180	NM_001172517	SATB2	SATB homeobox 2
chr6_-_88917600	1.149	NM_001160260	CNR1	cannabinoid receptor 1 (brain)
chr3_+_99484421	1.105	NM_001005482	OR5H2	olfactory receptor, family 5, subfamily H, member 2
chr17_+_57811645	1.094	NM_173503	EFCAB3	EF-hand calcium binding domain 3
chr10_+_124141808	1.078	NM_021622	PLEKHA1	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
chr1_+_246635918	1.076	NM_030904	OR2T1	olfactory receptor, family 2, subfamily T, member 1
chrX_+_135210787	1.065	NM_153834	GPR112	G protein-coupled receptor 112
chr12_-_9123126	1.046		A2M	alpha-2-macroglobulin
chr9_-_28709302	1.028	NM_152570	LINGO2	leucine rich repeat and Ig domain containing 2
chr18_+_59571256	1.015	NM_001040147	SERPINB7	serpin peptidase inhibitor, clade B (ovalbumin), member 7
chrX_+_87888881	1.011	NM_001184771 NM_033048	CPXCR1	CPX chromosome region, candidate 1
chr3_+_99350859	1.010	NM_001005514	OR5H14	olfactory receptor, family 5, subfamily H, member 14
chr20_+_16312	1.006	NM_153325	DEFB125	defensin, beta 125
chr5_-_58331515	1.003	NM_001197223	PDE4D	phosphodiesterase 4D, cAMP-specific
chr10_-_98315090	1.003		TM9SF3	transmembrane 9 superfamily member 3
chr3_-_174341653	0.989	NM_031955	SPATA16	spermatogenesis associated 16
chr19_-_49523747	0.983		ZFP112	zinc finger protein 112 homolog (mouse)
chr4_+_70928718	0.970	NM_000200	HTN3	histatin 3
chr10_-_27097782	0.968		ABI1	abl-interactor 1
chr1_+_93072947	0.967		RPL5	ribosomal protein L5
chr16_+_74868676	0.957	NM_033401	CNTNAP4	contactin associated protein-like 4
chr4_+_100714995	0.950		MTTP	microsomal triglyceride transfer protein
chr6_+_64344307	0.936		PTP4A1	protein tyrosine phosphatase type IVA, member 1
chr3_+_63403792	0.933	NM_144642	SYNPR	synaptoporin
chr18_+_61569136	0.927	NM_004361	CDH7	cadherin 7, type 2
chr9_-_13240313	0.914	NM_003829	MPDZ	multiple PDZ domain protein
chr9_-_21177529	0.906	NM_021068	IFNA4	interferon, alpha 4
chr8_-_93177057	0.902	NM_001198625 NM_001198626 NM_001198627 NM_001198631 NM_001198634 NM_001198679	RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr14_-_106240998	0.900		IGHV1-69 IGHG1	immunoglobulin heavy variable 1-69 immunoglobulin heavy constant gamma 1 (G1m marker)
chr6_-_138862273	0.898
chr14_-_106241445	0.885		IGHV4-31 IGHV1-69 IGHA1 IGHG1 IGHG3 IGHM	immunoglobulin heavy variable 4-31 immunoglobulin heavy variable 1-69 immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant gamma 1 (G1m marker) immunoglobulin heavy constant gamma 3 (G3m marker) immunoglobulin heavy constant mu
chr1_+_81544432	0.884		LPHN2	latrophilin 2
chr9_-_85773899	0.883		HNRNPK	heterogeneous nuclear ribonucleoprotein K
chr2_+_89715037	0.883
chr11_-_56067308	0.868	NM_001005245	OR5M11	olfactory receptor, family 5, subfamily M, member 11
chr10_+_91127792	0.845	NM_001010987	IFIT1B	interferon-induced protein with tetratricopeptide repeats 1B
chr6_+_88021644	0.839		ZNF292	zinc finger protein 292
chr2_-_231697999	0.830	NM_000867	HTR2B	5-hydroxytryptamine (serotonin) receptor 2B
chr8_+_32698892	0.828	NM_001159996	NRG1	neuregulin 1
chr12_+_7755316	0.828	NM_199286	DPPA3 STELLAR	developmental pluripotency associated 3 developmental pluripotency associated 3 pseudogene
chr14_-_106330781	0.822		IGHV5-78	immunoglobulin heavy variable 5-78 pseudogene
chr15_+_22772545	0.814		SNRPN	small nuclear ribonucleoprotein polypeptide N
chr4_-_165338312	0.799	NM_012403	ANP32C	acidic (leucine-rich) nuclear phosphoprotein 32 family, member C
chr4_-_74307637	0.793		ANKRD17	ankyrin repeat domain 17
chr5_+_27508139	0.792		LOC643401	hypothetical protein LOC643401
chr4_-_91979113	0.786	NM_183049	TMSL3	thymosin-like 3
chrX_+_141941369	0.782	NM_001009613	SPANXN4	SPANX family, member N4
chr3_-_87408301	0.778	NM_000306 NM_001122757	POU1F1	POU class 1 homeobox 1
chr18_+_74957475	0.769
chr9_-_21156609	0.759	NM_002175	IFNA21	interferon, alpha 21
chr3_+_89239363	0.745	NM_005233 NM_182644	EPHA3	EPH receptor A3
chr5_+_140235114	0.743	NM_018903 NM_031864	PCDHA12	protocadherin alpha 12
chr13_-_69580459	0.736	NM_020866	KLHL1	kelch-like 1 (Drosophila)
chr14_-_105712630	0.722		IGHV4-31 IGHA1 IGHA2 IGHG1	immunoglobulin heavy variable 4-31 immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant alpha 2 (A2m marker) immunoglobulin heavy constant gamma 1 (G1m marker)
chr18_+_61568825	0.722		CDH7	cadherin 7, type 2
chr2_-_37397669	0.722	NM_005813	PRKD3	protein kinase D3
chr21_-_30884586	0.721	NM_001164434	KRTAP22-2	keratin associated protein 22-2
chr12_+_63090008	0.720		XPOT	exportin, tRNA (nuclear export receptor for tRNAs)
chr6_-_116553918	0.717	NM_000493	COL10A1	collagen, type X, alpha 1
chr2_+_191009265	0.703		MFSD6	major facilitator superfamily domain containing 6
chr10_-_74863303	0.702	NM_001024593	ZMYND17	zinc finger, MYND-type containing 17
chr2_+_211166323	0.702	NM_001122634	CPS1	carbamoyl-phosphate synthase 1, mitochondrial
chr12_-_69600514	0.699		PTPRR	protein tyrosine phosphatase, receptor type, R
chr15_+_22652790	0.698	NM_022805	SNRPN	small nuclear ribonucleoprotein polypeptide N
chr13_-_98757634	0.681	NM_004951	GPR183	G protein-coupled receptor 183
chr4_+_184257337	0.680	NM_024949	WWC2	WW and C2 domain containing 2
chr10_-_45350804	0.680	NM_001002266	MARCH8	membrane-associated ring finger (C3HC4) 8
chr9_-_74757735	0.678	NM_000689	ALDH1A1	aldehyde dehydrogenase 1 family, member A1
chr3_+_190372456	0.666	NM_198485	TPRG1	tumor protein p63 regulated 1
chr3_+_99334230	0.663	NM_001005338	OR5H1	olfactory receptor, family 5, subfamily H, member 1
chr11_-_19038803	0.652	NM_054030	MRGPRX2	MAS-related GPR, member X2
chr3_-_69381995	0.652		FRMD4B	FERM domain containing 4B
chr1_+_168381811	0.641	NM_001136107	METTL11B	methyltransferase like 11B
chr9_-_14900992	0.640	NM_144966	FREM1	FRAS1 related extracellular matrix 1
chr9_+_111927601	0.640	NM_001136562	AKAP2	A kinase (PRKA) anchor protein 2
chr10_+_96512447	0.634	NM_000769	CYP2C19	cytochrome P450, family 2, subfamily C, polypeptide 19
chr2_-_219614481	0.630	NM_152389 NM_194302	CCDC108	coiled-coil domain containing 108
chr21_+_30937053	0.628	NM_001128077	KRTAP20-3	keratin associated protein 20-3
chr9_-_4142182	0.626	NM_152629	GLIS3	GLIS family zinc finger 3
chr3_+_109504021	0.625	NM_007072	HHLA2	HERV-H LTR-associating 2
chr11_-_6005546	0.621	NM_001001917	OR56A1	olfactory receptor, family 56, subfamily A, member 1
chr1_+_112740378	0.620
chr11_-_55987452	0.619	NM_001004743	OR5M9	olfactory receptor, family 5, subfamily M, member 9
chr11_+_55362802	0.617	NM_001005496	OR5D16	olfactory receptor, family 5, subfamily D, member 16
chr21_-_30583702	0.616	NM_001128598	KRTAP25-1	keratin associated protein 25-1
chr1_-_246503738	0.615	NM_001004695	OR2T33	olfactory receptor, family 2, subfamily T, member 33
chr3_+_44641505	0.615	NM_001024855 NM_006991	ZNF197	zinc finger protein 197
chr4_-_70861301	0.609	NM_001891	CSN2	casein beta
chr5_-_95794416	0.607	NM_000439	PCSK1	proprotein convertase subtilisin/kexin type 1
chr14_-_94677807	0.607	NM_030621	DICER1	dicer 1, ribonuclease type III
chr13_-_85271329	0.603	NM_032229	SLITRK6	SLIT and NTRK-like family, member 6
chrX_-_15312390	0.591	NM_004469	FIGF	c-fos induced growth factor (vascular endothelial growth factor D)
chr12_+_20854904	0.583	NM_019844	SLCO1B3	solute carrier organic anion transporter family, member 1B3
chr11_-_59390518	0.576	NM_001062	TCN1	transcobalamin I (vitamin B12 binding protein, R binder family)
chr14_+_71065794	0.575	NM_015556	SIPA1L1	signal-induced proliferation-associated 1 like 1
chr10_+_123913094	0.571	NM_006997 NM_206860	TACC2	transforming, acidic coiled-coil containing protein 2
chr3_-_153541468	0.563	NM_001123228	TMEM14E	transmembrane protein 14E
chr18_-_59462469	0.563	NM_002974	SERPINB4	serpin peptidase inhibitor, clade B (ovalbumin), member 4
chr8_+_17874128	0.558		PCM1	pericentriolar material 1
chr6_+_55147029	0.553	NM_001526	HCRTR2	hypocretin (orexin) receptor 2
chr2_-_87906400	0.553	NM_001078170	RGPD2	RANBP2-like and GRIP domain containing 2
chr18_-_35634247	0.552		LOC647946	hypothetical LOC647946
chr2_+_204509698	0.549	NM_012092	ICOS	inducible T-cell co-stimulator
chr2_-_233349469	0.547	NM_001172416 NM_001172417 NM_002242	KCNJ13	potassium inwardly-rectifying channel, subfamily J, member 13
chr14_-_106154332	0.544		LOC100126583 IGHG1	hypothetical LOC100126583 immunoglobulin heavy constant gamma 1 (G1m marker)
chr16_+_52081836	0.539		RBL2	retinoblastoma-like 2 (p130)
chr17_+_12564330	0.538	NM_001146313	MYOCD	myocardin
chr3_+_99370233	0.536	NM_001005515	OR5H15	olfactory receptor, family 5, subfamily H, member 15
chr4_+_100651183	0.533	NM_032149	C4orf17	chromosome 4 open reading frame 17
chr15_+_22781292	0.525		PAR5	Prader-Willi/Angelman syndrome-5
chr12_+_54106304	0.524	NM_001005183	OR6C76	olfactory receptor, family 6, subfamily C, member 76
chr15_+_22619886	0.524	NM_022806 NM_022807 NM_022808	SNRPN	small nuclear ribonucleoprotein polypeptide N
chr8_-_17797127	0.521	NM_147203 NM_201553 NM_004467 NM_201552	FGL1	fibrinogen-like 1
chrX_-_62697473	0.515		LOC92249	hypothetical LOC92249
chr10_+_118295417	0.511	NM_000936	PNLIP	pancreatic lipase
chr19_+_9132367	0.509
chr14_+_38720085	0.503		PNN	pinin, desmosome associated protein
chr6_-_56220274	0.497	NM_030820	COL21A1	collagen, type XXI, alpha 1
chr3_-_193928038	0.494	NM_004113	FGF12	fibroblast growth factor 12
chr4_-_45820686	0.493	NM_173536	GABRG1	gamma-aminobutyric acid (GABA) A receptor, gamma 1
chr16_+_31105579	0.492
chr6_-_119512035	0.492	NM_001100411	FAM184A	family with sequence similarity 184, member A
chr6_-_22410993	0.488	NM_001163558	PRL	prolactin
chr1_+_112740322	0.487	NM_018704	CTTNBP2NL	CTTNBP2 N-terminal like
chr4_+_70831387	0.487	NM_001025104 NM_001890	CSN1S1	casein alpha s1
chr11_-_35398077	0.483	NM_001195728	SLC1A2	solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr7_+_129057152	0.481	NM_001040110	NRF1	nuclear respiratory factor 1
chr19_-_62370667	0.478	NM_001012729	DUXA	double homeobox A
chr6_-_142451487	0.474	NM_002511	NMBR	neuromedin B receptor
chr1_+_112740380	0.472		LOC100129406 CTTNBP2NL	hypothetical protein LOC100129406 CTTNBP2 N-terminal like
chr14_-_20098929	0.472	NM_001001673 NM_001110356 NM_001110357 NM_001110358 NM_001110359 NM_001110360 NM_001110361	RNASE9	ribonuclease, RNase A family, 9 (non-active)
chr17_+_24394281	0.471		PIPOX	pipecolic acid oxidase
chr9_-_36365965	0.469		RNF38	ring finger protein 38
chr9_-_21218132	0.463	NM_021268	IFNA17	interferon, alpha 17
chr5_+_140751666	0.459	NM_014004 NM_032088	PCDHGA8	protocadherin gamma subfamily A, 8
chr13_-_102209422	0.458	NM_001146197	C13orf40	chromosome 13 open reading frame 40
chr2_+_166034402	0.453	NM_001172173	CSRNP3	cysteine-serine-rich nuclear protein 3
chr6_-_49862858	0.453	NM_138733	PGK2	phosphoglycerate kinase 2
chr16_+_82540172	0.450	NM_013370 NM_182980	OSGIN1	oxidative stress induced growth inhibitor 1
chr8_-_120720200	0.449	NM_001040092 NM_001130863 NM_006209	ENPP2	ectonucleotide pyrophosphatase/phosphodiesterase 2
chr3_+_51837608	0.447	NM_001085479	IQCF3	IQ motif containing F3
chr6_-_50045296	0.446	NM_001037729	DEFB113	defensin, beta 113
chr14_+_59934178	0.444
chr14_-_106137250	0.444
chrX_-_123925343	0.443	NM_001163278 NM_001163279 NM_014253	ODZ1	odz, odd Oz/ten-m homolog 1(Drosophila)
chr14_-_106149623	0.442
chr21_-_30836051	0.440	NM_181612	KRTAP19-6	keratin associated protein 19-6
chr14_-_74669864	0.440		TMED10	transmembrane emp24-like trafficking protein 10 (yeast)
chr12_+_38306238	0.438	NM_001031748	C12orf40	chromosome 12 open reading frame 40
chr4_-_101034689	0.437	NM_021970	LAMTOR3	late endosomal/lysosomal adaptor, MAPK and MTOR activator 3
chr21_+_30910614	0.433	NM_181615	KRTAP20-1	keratin associated protein 20-1
chr15_-_39151468	0.429		INO80	INO80 homolog (S. cerevisiae)
chr6_+_153113624	0.428	NM_003381 NM_194435	VIP	vasoactive intestinal peptide
chr1_-_158759606	0.426	NM_001184714 NM_001184715 NM_001184716 NM_052931	SLAMF6	SLAM family member 6
chr20_+_20296744	0.425	NM_002196	INSM1	insulinoma-associated 1
chr2_-_45648608	0.423		SRBD1	S1 RNA binding domain 1
chr14_-_62854315	0.422	NM_145171	GPHB5	glycoprotein hormone beta 5
chr1_-_246823691	0.421	NM_001004693	OR2T10	olfactory receptor, family 2, subfamily T, member 10
chr6_+_131190237	0.418	NM_001195597	LOC285733	hypothetical LOC285733
chr10_+_95838801	0.418	NM_001165979	PLCE1	phospholipase C, epsilon 1
chr17_-_43254117	0.416		OSBPL7	oxysterol binding protein-like 7
chr12_-_119733062	0.415		SPPL3	signal peptide peptidase 3
chr11_+_82078217	0.412
chr4_+_146820805	0.405	NM_001080531	C4orf51	chromosome 4 open reading frame 51
chr10_+_104995633	0.404	NM_001143909	LOC729020	rcRPE
chr12_+_1596482	0.403	NM_030775	WNT5B	wingless-type MMTV integration site family, member 5B
chr1_+_195213289	0.402	NM_030787	CFHR5	complement factor H-related 5
chr7_-_122126422	0.400	NM_139175	RNF133	ring finger protein 133
chr8_-_146173531	0.397		ZNF252	zinc finger protein 252
chrX_+_7147471	0.397	NM_000351	STS	steroid sulfatase (microsomal), isozyme S

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
3.72	2.99e-19	GO:0007606	sensory perception of chemical stimulus
3.81	4.98e-18	GO:0007608	sensory perception of smell
2.59	3.55e-13	GO:0007600	sensory perception
2.06	1.43e-10	GO:0050877	neurological system process
1.35	1.98e-08	GO:0050896	response to stimulus
1.81	6.15e-08	GO:0003008	system process
1.31	2.12e-04	GO:0032501	multicellular organismal process
4.74	4.68e-03	GO:0015718	monocarboxylic acid transport

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.40	4.38e-07	GO:0071944	cell periphery
1.40	4.89e-07	GO:0005886	plasma membrane
1.52	1.33e-04	GO:0005576	extracellular region
1.60	1.97e-02	GO:0044421	extracellular region part
1.68	2.59e-02	GO:0005615	extracellular space

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
4.00	7.40e-20	GO:0004984	olfactory receptor activity
2.64	2.59e-15	GO:0004930	G-protein coupled receptor activity
2.22	4.56e-14	GO:0004888	transmembrane receptor activity
1.92	1.50e-11	GO:0004872	receptor activity
1.79	5.53e-11	GO:0004871	signal transducer activity
1.79	5.53e-11	GO:0060089	molecular transducer activity