Motif ID: POU5F1_SOX2{dimer}.p2

Z-value: 1.554


Transcription factors associated with POU5F1_SOX2{dimer}.p2:

Gene SymbolEntrez IDGene Name
POU5F1 5460 POU class 5 homeobox 1
SOX2 6657 SRY (sex determining region Y)-box 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
POU5F1chr6_-_31246159-0.449.0e-02Click!
SOX2chr3_+_1829127690.332.1e-01Click!


Activity profile for motif POU5F1_SOX2{dimer}.p2.

activity profile for motif POU5F1_SOX2{dimer}.p2


Sorted Z-values histogram for motif POU5F1_SOX2{dimer}.p2

Sorted Z-values for motif POU5F1_SOX2{dimer}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of POU5F1_SOX2{dimer}.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_-_215949566 4.070 FN1
fibronectin 1
chr9_-_21340885 2.552 NM_021002
 IFNA6
interferon, alpha 6
chr2_-_215998181 2.166 FN1
fibronectin 1
chr4_-_21155376 2.098 NM_001035004
 KCNIP4
Kv channel interacting protein 4
chr12_-_10846435 2.068 NM_023919
 TAS2R7
taste receptor, type 2, member 7
chr6_-_66346417 2.037 NM_198283
 EYS
eyes shut homolog (Drosophila)
chr18_+_50646616 1.947 NM_004163
 RAB27B
RAB27B, member RAS oncogene family
chr12_+_103221590 1.928 NM_001008394
 EID3
EP300 interacting inhibitor of differentiation 3
chr9_+_21399132 1.906 NM_002170
 IFNA8
interferon, alpha 8
chr7_+_90176647 1.788 NM_012395
 CDK14
cyclin-dependent kinase 14
chr4_-_149577404 1.769


chr18_-_56190980 1.693 NM_005912
 MC4R
melanocortin 4 receptor
chr9_-_21229975 1.659 NM_002172
 IFNA14
interferon, alpha 14
chr4_+_114433551 1.644 ANK2
ankyrin 2, neuronal
chr12_-_88573949 1.610 NM_001001323
NM_001682
 ATP2B1

ATPase, Ca++ transporting, plasma membrane 1

chr3_-_56784634 1.539 NM_001128616
 ARHGEF3
Rho guanine nucleotide exchange factor (GEF) 3
chr2_+_113479919 1.506 NM_014440
 IL1F6
interleukin 1 family, member 6 (epsilon)
chr9_-_21197141 1.494 NM_002171
 IFNA10
interferon, alpha 10
chr13_+_96592051 1.481 MBNL2
muscleblind-like 2 (Drosophila)
chr11_-_121492010 1.397 NM_001001786
 BLID
BH3-like motif containing, cell death inducer

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 8 of 8 entries
enrichment   p-value GO term description
4.74 4.68e-03 GO:0015718 monocarboxylic acid transport
3.81 4.98e-18 GO:0007608 sensory perception of smell
3.72 2.99e-19 GO:0007606 sensory perception of chemical stimulus
2.59 3.55e-13 GO:0007600 sensory perception
2.06 1.43e-10 GO:0050877 neurological system process
1.81 6.15e-08 GO:0003008 system process
1.35 1.98e-08 GO:0050896 response to stimulus
1.31 2.12e-04 GO:0032501 multicellular organismal process

Gene overrepresentation in compartment category:

Showing 1 to 5 of 5 entries
enrichment   p-value GO term description
1.68 2.59e-02 GO:0005615 extracellular space
1.60 1.97e-02 GO:0044421 extracellular region part
1.52 1.33e-04 GO:0005576 extracellular region
1.40 4.38e-07 GO:0071944 cell periphery
1.40 4.89e-07 GO:0005886 plasma membrane

Gene overrepresentation in function category:

Showing 1 to 6 of 6 entries
enrichment   p-value GO term description
4.00 7.40e-20 GO:0004984 olfactory receptor activity
2.64 2.59e-15 GO:0004930 G-protein coupled receptor activity
2.22 4.56e-14 GO:0004888 transmembrane receptor activity
1.92 1.50e-11 GO:0004872 receptor activity
1.79 5.53e-11 GO:0004871 signal transducer activity
1.79 5.53e-11 GO:0060089 molecular transducer activity